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The calcium endocrine system.

S Sethi1, T C Aw

  • 1Department of Laboratory Medicine, National University Hospital.

Annals of the Academy of Medicine, Singapore
|July 1, 1989
PubMed
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Calcium is vital for many bodily functions. New research reveals insights into vitamin D

Area of Science:

  • Physiology
  • Molecular Biology
  • Endocrinology

Background:

  • Calcium's role as a physiological modulator is established.
  • Understanding calcium's subcellular and molecular aspects is ongoing.
  • Emerging research highlights new functions of vitamin D.

Purpose of the Study:

  • To explore novel aspects of vitamin D metabolism and function.
  • To investigate the feedback mechanisms in vitamin D conversion.
  • To highlight the clinical relevance of vitamin D's diverse roles.

Main Methods:

  • Review of current literature on calcium and vitamin D.
  • Analysis of hepatocellular uptake mechanisms for vitamin D.
  • Examination of hepatic conversion pathways of vitamin D.

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Main Results:

  • New knowledge on vitamin D uptake by liver cells.
  • Potential feedback control of vitamin D conversion by its active form.
  • Identification of diverse and clinically applicable vitamin D functions.

Conclusions:

  • Vitamin D metabolism and function are complex and multifaceted.
  • Active vitamin D may regulate its own hepatic conversion.
  • Vitamin D possesses significant and emerging clinical applications.