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Updated: Apr 19, 2026
An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
USA endometrial cancer projections to 2030: should we be concerned?
M Aamir Sheikh1, Andrew D Althouse, Kyle E Freese
1Department of OB/GYN & Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh School of Medicine, M240 Scaife Hall, 3550 Terrace St, Pittsburgh, PA 15261, USA.
Aim:
As the incidence of endometrial cancer (EC) increased considerably since 2007, this study aimed to project the burden of EC to the year 2030.
Methods:
Multivariate linear regression was used to project EC incidence by modeling trends in EC incidence from 1990 to 2013, while accounting for temporal changes in obesity, hysterectomy and smoking.
Results:
The best-fitting model predicting EC rates included a time effect plus effects for hysterectomy (12-year lag), severe obesity (3-year lag) and smoking (9-year lag). The best-fitting model projected an increase to 42.13 EC cases per 100,000 by the year 2030, a 55% increase over 2010 EC rates.
Conclusion:
The projected increase of EC over next 16 years indicates the need for close monitoring of EC trends.
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