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Amniotic band syndrome: a single-institutional experience
Corey W Iqbal1, S Christopher Derderian, Yvonne Cheng
1Children's Mercy Hospital Fetal Health Center, Kansas City, Mo., USA.
Fetal Diagnosis and Therapy
|December 23, 2014
Summary
Amniotic band syndrome (ABS) most often affects extremities. Fetoscopic lysis can be effective for select cases, but umbilical cord involvement is linked to poorer outcomes in ABS patients.
Area of Science:
- Medical research
- Obstetrics and Gynecology
- Fetal Medicine
Background:
- Amniotic band syndrome (ABS) is a rare congenital disorder.
- Understanding its natural history and outcomes is crucial for patient management.
Purpose of the Study:
- To review a single institution's experience with amniotic band syndrome.
- To define the natural history and outcomes of ABS.
Main Methods:
- Retrospective analysis of patients diagnosed with ABS between 1997 and 2012.
- Evaluation of patient demographics, affected sites, interventions, and survival rates.
Main Results:
- Twenty-eight patients were diagnosed with ABS.
- Extremities were the most commonly affected site (n=20).
- Overall survival, excluding terminations, was 74%; cord involvement was associated with higher mortality.
Conclusions:
- ABS frequently involves extremities, and membrane disruption is not always evident.
- Fetoscopic amniotic band lysis is a viable option for select patients.
- Umbilical cord involvement in ABS necessitates careful consideration due to its association with adverse outcomes.
