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Pediatric MR enterography: technique and approach to interpretation-how we do it
Brett J Mollard1, Ethan A Smith, Jonathan R Dillman
1From the Department of Radiology (B.J.M., E.A.S., J.R.D.), Section of Pediatric Radiology (E.A.S., J.R.D.), University of Michigan Health System, C.S. Mott Children's Hospital, 1540 E. Hospital Dr., SPC 4252, Ann Arbor, MI 48109-4252.
Insights
Magnetic resonance enterography (MRE) is a key tool for diagnosing pediatric inflammatory bowel disease (IBD) without radiation. This review details MRE interpretation, protocol, and its role in assessing IBD activity and complications.
Area of Science:
- Pediatric Radiology
- Gastroenterology Imaging
- Inflammatory Bowel Disease (IBD) Diagnostics
Background:
- Magnetic resonance (MR) enterography is a vital imaging technique for pediatric patients, primarily evaluating inflammatory bowel disease (IBD).
- It offers an alternative to radiation-based imaging, crucial for children and adolescents.
- MRE assesses bowel, mesentery, soft tissues, and extraintestinal manifestations of IBD.
Purpose of the Study:
- To provide radiologists with a systematic approach for reviewing and interpreting pediatric MR enterography in suspected or confirmed IBD cases.
- To illustrate common and uncommon imaging findings associated with pediatric IBD.
- To present a clinically successful pediatric MRE protocol and discuss indications.
Main Methods:
- Review article synthesizing current knowledge and clinical experience.
- Focus on a systematic approach to MRE interpretation in pediatric IBD.
- Inclusion of a standardized pediatric MRE protocol and discussion of clinical indications.
Main Results:
- MRE is effective for initial diagnosis, particularly small bowel Crohn disease.
- It serves as a radiologic biomarker for assessing inflammatory activity and response to therapy.
- MRE identifies disease complications such as strictures, fistulae, and abscesses.
Conclusions:
- MR enterography is an essential, non-ionizing imaging modality for pediatric IBD evaluation.
- A systematic approach and standardized protocol enhance diagnostic accuracy and patient management.
- MRE plays a crucial role in monitoring disease activity, treatment response, and complications.
Abstract:
Magnetic resonance (MR) enterography is an increasingly important pediatric imaging modality that is most often used to evaluate inflammatory bowel disease ( IBD inflammatory bowel disease ), while sparing children and adolescents from potential risks of ionizing radiation exposure. MR enterography allows for evaluation of the bowel lumen and wall, adjacent mesentery and soft tissues, as well as a variety of extraintestinal abdominopelvic IBD inflammatory bowel disease manifestations. While MR enterography can be used to initially confirm the diagnosis of IBD inflammatory bowel disease , particularly small bowel Crohn disease, it has also proven useful in assessing the degree inflammatory activity over time, serving as a radiologic biomarker for response to medical therapy, and identifying a variety of disease-related complications, including strictures, fistulae, and abscesses. The purpose of this review article is to provide radiologists with a systematic approach for MR enterography review and interpretation in children and adolescents with known or suspected of having IBD inflammatory bowel disease and to illustrate both common and infrequent but important imaging findings. Additionally, the authors will present their well-established and clinically successful pediatric MR enterography protocol, up-to-date clinical indications for MR enterography, and briefly mention the role of MR enterography in assessing non- IBD inflammatory bowel disease abnormalities affecting the bowel. Online supplemental material is available for this article .
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