[Endonasal removal of pituitary growth hormone-adenoma: report of 56 cases]

Fifty-six cases of pituitary GH-adenoma removed by endonasal method are reported. In 50 cases, plasma hGH decreased postoperatively. According to biological evaluation, 18 patients were cured, 21 were improved and 17 presented no change. Postoperative high hGH (greater than or equal to 5 ng/ml) indicated that there were some residual functioning tumor cells in the Sella. Such cases must be followed up regularly in order to assess when and what treatment should be given. Postoperative radiation usually raises the curability of acromegaly. Endonasal method is simple, effective and less injurious to the neighboring structure of the nose.