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Related Concept Videos

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Related Experiment Video

Updated: Apr 19, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
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Evolution of left ventricular function in the preterm infant.

Akiko Hirose1, Nee S Khoo1, Khalid Aziz2

  • 1Fetal & Neonatal Cardiology Program, Department of Pediatrics, Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
|December 24, 2014
PubMed
Summary
This summary is machine-generated.

Preterm infants show normal systolic function but impaired diastolic function, with increased reliance on atrial contraction, persisting even near term. These findings are crucial for managing preterm infants and understanding long-term heart health.

Keywords:
EchocardiographyMyocardial functionPremature infant

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Area of Science:

  • Neonatal cardiology
  • Pediatric echocardiography
  • Cardiovascular physiology

Background:

  • Preterm infants (<30 weeks gestational age) face unique cardiovascular challenges.
  • Evaluating left ventricular function is critical for neonatal care.

Purpose of the Study:

  • To assess left ventricular systolic and diastolic function in preterm infants.
  • To compare function between preterm and term infants using advanced echocardiography.

Main Methods:

  • Prospective enrollment of 30 stable preterm infants (<30 weeks GA).
  • Echocardiography (conventional, tissue Doppler, speckle-tracking) at 28 days and near term.
  • Comparison with 30 healthy term infants.

Main Results:

  • Preterm infants showed impaired diastolic function (decreased E/A, e'/a' ratios; increased E/e') at 28 days and near term.
  • Systolic function (fractional shortening, ejection fraction, strain) was comparable to term infants.
  • No correlation between heart rate and diastolic parameters was observed.

Conclusions:

  • Clinically stable preterm infants exhibit normal systolic function but altered diastolic function.
  • Increased dependence on atrial contraction for diastolic filling persists near term.
  • Findings may inform preterm infant management and long-term cardiac health outcomes.