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Published on: April 26, 2024
Depressive symptoms and spiritual wellbeing in asymptomatic heart failure patients
Paul J Mills1, Kathleen Wilson, Navaid Iqbal
1Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr. #0804, La Jolla, CA, 92093-0804, USA, pmills@ucsd.edu.
Insights
Spiritual wellbeing, including meaning and peace, is linked to fewer depressive symptoms in heart failure patients. Interventions targeting spiritual health may help manage depression in this population.
Area of Science:
- Cardiology
- Psychiatry
- Psychology
Background:
- Depression negatively impacts prognosis in symptomatic heart failure.
- Spiritual wellness may act as a protective factor against depressive symptoms in certain populations.
- Heart failure patients often experience comorbidities like depression, fatigue, and sleep disturbances.
Purpose of the Study:
- To examine the associations among depressive symptoms, spiritual wellbeing, sleep, fatigue, functional capacity, and inflammatory biomarkers.
- To identify factors associated with fewer depressive symptoms in individuals with asymptomatic stage B heart failure.
- To explore the role of spiritual wellbeing subscales (faith, meaning, peace) in relation to depressive symptoms.
Main Methods:
- A study involving 132 men and women with asymptomatic stage B heart failure.
- Multiple regression analysis was used to predict depressive symptoms.
- Beck Depression Inventory and spiritual wellbeing scales were utilized.
Main Results:
- Approximately 32% of patients exhibited clinically relevant depressive symptoms.
- Fewer depressive symptoms were significantly associated with a lower inflammatory score, less fatigue, better sleep, and higher spiritual wellbeing.
- The meaning and peace subscales of spiritual wellbeing, but not faith, were independently linked to fewer depressive symptoms.
Conclusions:
- Spiritual wellbeing, particularly its meaning and peace components, is a significant factor associated with reduced depressive symptoms in asymptomatic heart failure.
- Interventions focused on enhancing spiritual wellbeing, specifically meaning and peace, could be a viable treatment strategy for managing depression in this patient group.
- Addressing spiritual health may offer a novel therapeutic avenue for improving mental health outcomes in individuals with early-stage heart failure.
Abstract:
Depression adversely predicts prognosis in individuals with symptomatic heart failure. In some clinical populations, spiritual wellness is considered to be a protective factor against depressive symptoms. This study examined associations among depressive symptoms, spiritual wellbeing, sleep, fatigue, functional capacity, and inflammatory biomarkers in 132 men and women with asymptomatic stage B heart failure (age 66.5 years ± 10.5). Approximately 32 % of the patients scored ≥10 on the Beck Depression Inventory, indicating potentially clinically relevant depressive symptoms. Multiple regression analysis predicting fewer depressive symptoms included the following significant variables: a lower inflammatory score comprised of disease-relevant biomarkers (p < 0.02), less fatigue (p < 0.001), better sleep (p < 0.04), and more spiritual wellbeing (p < 0.01) (overall model F = 26.6, p < 0.001, adjusted R square = 0.629). Further analyses indicated that the meaning (p < 0.01) and peace (p < 0.01) subscales, but not the faith (p = 0.332) subscale, of spiritual wellbeing were independently associated with fewer depressive symptoms. Interventions aimed at increasing spiritual wellbeing in patients lives, and specifically meaning and peace, may be a potential treatment target for depressive symptoms asymptomatic heart failure.
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