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Updated: Apr 19, 2026
Functional Characterization of Carboxylesterases in Insecticide Resistant House Flies, Musca Domestica
Published on: August 23, 2018
Progressive adaptation of a CpGV isolate to codling moth populations resistant to CpGV-M
Benoît Graillot1, Marie Berling2, Christine Blachere-López3
1LGEI, Ecole des Mines d'Alès, Institut Mines-Telecom et Université de Montpellier Sud de France, 6, Avenue de Clavières, 30319 Alès, France. samantha.besse@arysta.com.
Abstract:
The NPP-R1 isolate of CpGV is able to replicate on CpGV-M-resistant codling moths. However, its efficacy is not sufficient to provide acceptable levels of control in natural (orchard) conditions. A laboratory colony derived from resistant codling moths was established, which exhibited a homogeneous genetic background and a resistance level more than 7000 fold. By successive cycles of replication of NPP-R1 in this colony, we observed a progressive increase in efficacy. After 16 cycles (isolate 2016-r16), the efficacy of the virus isolate was equivalent to that of CpGV-M on susceptible insects. This isolate was able to control both CpGV-M-susceptible and CpGV-M-resistant insects with similar efficacy. No reduction in the levels of occlusion body production in susceptible larvae was observed for 2016-r16 compared to CpGV-M.
