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Published on: December 5, 2025
[Evolution of non-invasive ventilation in acute bronchiolitis]
B Toledo del Castillo1, S N Fernández Lafever1, C López Sanguos1
1Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Instituto de Investigación del Hospital General Universitario Gregorio Marañón, Madrid, Red de Salud Maternoinfantil y del Desarrollo (Red SAMID), Madrid, España.
Insights
Non-invasive ventilation (NIV) use increased significantly in pediatric intensive care units for bronchiolitis, leading to reduced invasive ventilation (IV) and shorter hospital stays.
Area of Science:
- Pediatric Intensive Care
- Respiratory Medicine
- Critical Care
Background:
- Acute bronchiolitis is a common cause of pediatric intensive care unit (PICU) admission.
- Ventilatory support, including non-invasive ventilation (NIV) and invasive ventilation (IV), is crucial for managing severe cases.
Purpose of the Study:
- To analyze the 12-year trend in the utilization of NIV and IV for pediatric patients with acute bronchiolitis.
- To compare ventilation strategies and outcomes between the first and second halves of the study period.
Main Methods:
- Retrospective observational study of 196 children admitted to the PICU for acute bronchiolitis between 2001 and 2012.
- Analysis of demographic data, ventilation methods (NIV vs. IV), and clinical outcomes.
- Comparison of data from the first six years (2001-2006) versus the last six years (2007-2012).
Main Results:
- NIV use increased from 79.4% to 100%, while IV use decreased from 46% to 22.6% over the study period.
- Continuous positive airway pressure and nasopharyngeal tubes were common, with increased use of bi-level NIV and nasal cannulas in the latter period.
- Median duration of IV was 9.5 days, NIV was 3 days, and PICU length of stay was 7 days, with a shorter stay in the second period.
Conclusions:
- The increasing adoption of NIV for bronchiolitis in the PICU correlated with a decline in IV use.
- This shift towards NIV was associated with a reduced length of PICU stay.
Objectives:
The aim of the study was to analyse the evolution, over a12-year period, of the use of non-invasive (NIV) and invasive ventilation (IV) in children admitted to a Paediatric Intensive Care Unit (PICU) due to acute bronchiolitis.
Patients And Methods:
A retrospective observational study was performed including all children who were admitted to the PICU requiring NIV or IV between 2001 and 2012. Demographic characteristics, ventilation assistance and clinical outcome were analysed. A comparison was made between the first six years and the last 6 years of the study.
Results:
A total of 196 children were included; 30.1% of the subjects required IV and 93.3% required NIV. The median duration of IV was 9.5 days and NIV duration was 3 days. The median PICU length of stay was 7 days, and 2% of the patients died. The use of NIV increased from 79.4% in first period to 100% in the second period (P<.0001) and IV use decreased from 46% in first period to 22.6% in the last 6 years (P<.0001). Continuous positive airway pressure and nasopharyngeal tube were the most frequently used modality and interface, although the use of bi-level non-invasive ventilation (P<.001) and of nasal cannulas significantly increased (P<.0001) in the second period, and the PICU length of stay was shorter (P=.011).
Conclusion:
The increasing use of NIV in bronchiolitis in our PICU during the last 12 years was associated with a decrease in the use of IV and length of stay in the PICU.
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