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Updated: Apr 19, 2026
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
[Prognostic analyses of occult breast cancer]
Xiaomeng Hao1, Sheng Zhang1, Jingjing Liu1
1Third Department of Breast Cancer, China Tianjin Breast Cancer Prevention, Treatment Research Center, Tianjin Medical University Cancer Institute & Hospital; Key Laboratory of Breast Cancer Prevention and Therapy of Ministry of Education; Key Laboratory of Cancer Prevention & Therapy, Tianjin 300060, China.
Objective:
To explore the prognosis of occult breast cancer.
Methods:
From January 1978 to December 2008, retrospective analyses were conducted for 205 female patients with axillary lymph node metastasis from an unknown primary source.
Results:
During a median follow-up time of 61 (4-158) months, the 5 and 10-year rates of disease-free survival (DFS) were 63.5% and 39.8% respectively. The median overall survival (OS) was 10 years. And the 5 and 10-year OS were 79.8% and 49.4% respectively. Significant differences existed in medical history, family history, estrogen receptor (ER), human epidermal growth factor receptor-2 (HER-2), infiltration of soft tissue, surgical option, neoadjuvant chemotherapy, chemotherapy, and radiotherapy with DFS of occult breast cancer (P < 0.05). The most important determinants of DFS and OS were ER, infiltration of soft tissue and neoadjuvant chemotherapy (P < 0.05).
Conclusion:
Radical mastectomy should be performed instead of modified radical mastectomy to improve the patient quality of life.
