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Related Concept Videos

Genomics02:02

Genomics

42.0K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
42.0K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Ribosome Profiling02:24

Ribosome Profiling

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Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
4.4K
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

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Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
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Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

5.0K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
5.0K
The Central Dogma01:20

The Central Dogma

35.9K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
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Updated: Apr 19, 2026

Polysome Purification from Soybean Symbiotic Nodules
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Genomics and the challenging translation into conservation practice.

Aaron B A Shafer1, Jochen B W Wolf1, Paulo C Alves2

  • 1Uppsala University, Ecology and Genetics, Evolutionary Biology Centre, 75236 Uppsala, Sweden.

Trends in Ecology & Evolution
|December 24, 2014
PubMed
Summary

Genomic data offers powerful conservation insights but faces challenges. Infrastructure, methods, and data sharing must advance to bridge the gap between research and practical biodiversity conservation.

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Area of Science:

  • Conservation genetics
  • Genomics
  • Biodiversity research

Background:

  • Global biodiversity loss is accelerating.
  • Genomic approaches can enhance conservation genetics, offering new insights.
  • Current genomic applications are limited to academic research, creating a gap.

Purpose of the Study:

  • To highlight the challenges in applying genomic research to conservation practice.
  • To identify necessary advancements for realizing the conservation potential of genomics.

Main Methods:

  • Review of current challenges in genomic data generation and analysis for conservation.
  • Identification of infrastructure, methodological, and dissemination needs.

Main Results:

  • Genomic data generation, analysis, and interpretation remain significant hurdles.
  • A gap exists between academic genomic research and practical conservation management.

Conclusions:

  • Realizing the conservation potential of genomics requires infrastructure modification.
  • Methodological maturation, analytical pipeline development, and case study dissemination are crucial for practitioners.