[Intracellular distribution of nucleotide sequences, homologous to mobile dispersed genes]

Full-size hybrid RNA-DNA molecules of mdg1, mdg3 and copia have been discovered in cultured cells of Drosophila. The intracellular distribution of these molecules is considered. Hybrid molecules are found both in the nuclei and cytoplasm, the latter comprising the major portion of molecules. The membrane subcellular fraction enriched by poly(A) RNA and poly(A) RNA-DNA molecules of retretransposons is isolated from cytoplasm. The full-size linear double-stranded DNA of mdg1 is found in the same fraction. The data obtained make it possible to suppose that the process of reverse transcription on the mdg RNA is the way of regulation of mdg expression in the cell.