Related Experiment Video
Updated: Apr 19, 2026

Author Spotlight: Advancing In Vitro Blood Cell Production with Single-Cell Multiomics and Functional Genomics
Published on: March 15, 2024
Perioperative neonatal and paediatric blood transfusion
Avnish Bharadwaj1, Mamta Khandelwal2, Suresh Kumar Bhargava3
1Department of Anesthesiology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, India.
Insights
Perioperative blood management in pediatric surgery is crucial. Preoperative evaluation, anemia correction, and careful blood loss monitoring ensure optimal patient outcomes.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Transfusion Medicine
Background:
- Paediatric patients frequently need blood or blood components during surgery.
- Major pediatric surgeries with significant blood loss risk require thorough preoperative assessment.
Purpose of the Study:
- To outline a protocol for perioperative blood management in pediatric surgical patients.
- To emphasize the importance of preoperative evaluation and intraoperative monitoring.
Main Methods:
- Pre-operative assessment including anemia correction based on patient status.
- Calculation of Maximum Allowable Blood Loss (MABL).
- Intraoperative monitoring of blood loss and protocol-based transfusion management.
Main Results:
- Ensuring adequate blood and component availability.
- Maintaining appropriate volemia and adhering to transfusion triggers.
- Achieving early hemostasis through judicious use of blood products and agents.
Conclusions:
- Comprehensive perioperative blood management is essential for pediatric surgical patients.
- Preoperative optimization and intraoperative vigilance improve surgical outcomes.
Abstract:
Paediatric patients undergoing surgical procedures commonly require some volume of blood or blood component replacement in the perioperative period. Paediatric patients undergoing major surgery associated with substantial blood loss should be evaluated pre-operatively. Pre-operative correction of anaemia may be done considering the age, plasma volume status, clinical status and comorbidities. Maximum allowable blood loss (MABL) for surgery must be calculated, and appropriate quantity of blood and blood components should be arranged. Intraoperative monitoring of blood loss should be done, and volume of transfusion should be calculated in a protocol based manner considering the volemia and the trigger threshold for transfusion for the patient and the MABL. Early haemostasis should be achieved by judicious administration of red blood cells, blood components and pharmacological agents.
More Related Videos
Related Concept Videos
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Kidney Transplant II: Surgical Procedure
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

