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Electron Spin Resonance Micro-imaging of Live Species for Oxygen Mapping
Published on: August 27, 2010
Electron spin resonance detection of oxygen-centred radicals in murine macrophages stimulated with bacterial
S K Jackson1, J M Stark, C C Rowlands
1Department of Medical Microbiology, University of Wales College of Medicine, Health Park, Cardiff, U.K.
Free Radical Biology & Medicine
|January 1, 1989
Abstract:
The production of oxygen radicals by Bacille-Calmette-Guerin primed mouse macrophages stimulated with bacterial endotoxin has been investigated. Superoxide radicals were spin-trapped in this system with dimethylpyrroline-N-oxide after a lag period of 20-40 minutes. The electron spin resonance signals due to the superoxide radical adduct could be inhibited by superoxide dismutase but not by catalase.
