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Sleep-disordered breathing in patients with post-traumatic stress disorder
Philippe Jaoude1, Leah N Vermont, Jahan Porhomayon
11 The Veterans Affairs Western New York Healthcare System, Buffalo, New York.
Annals of the American Thoracic Society
|December 24, 2014
Summary
Post-traumatic stress disorder (PTSD) and sleep-disordered breathing (SDB) frequently coexist, impacting sleep and quality of life. Research suggests an association, but mechanisms and treatments require further investigation for better patient outcomes.
Area of Science:
- Psychiatry
- Sleep Medicine
- Clinical Research
Background:
- Post-traumatic stress disorder (PTSD) and sleep-disordered breathing (SDB) are prevalent conditions often affecting the same patients.
- Both PTSD and SDB significantly impair sleep quality and overall quality of life.
- A literature review confirms a strong association between PTSD and SDB in various populations.
Purpose of the Study:
- To review the literature on the association between PTSD and SDB.
- To explore the potential mechanisms linking these two disorders.
- To identify diagnostic and therapeutic challenges and suggest future research directions.
Main Methods:
- Critical review of existing scientific literature.
- Analysis of studies examining the co-occurrence of PTSD and SDB.
- Synthesis of findings on shared symptoms, potential mechanisms, and treatment outcomes.
Main Results:
- A significant association exists between PTSD and SDB, irrespective of combat exposure.
- The precise mechanisms linking PTSD and SDB remain unclear, with sleep fragmentation and neuroendocrine pathways implicated.
- Diagnostic and therapeutic approaches for coexisting PTSD and SDB present challenges.
- Continuous positive airway pressure (CPAP) therapy shows potential in mitigating PTSD symptoms, but adherence is often poor.
Conclusions:
- The comorbidity of PTSD and SDB necessitates novel diagnostic and therapeutic strategies.
- Improving adherence to CPAP therapy is crucial for patients with comorbid PTSD and SDB.
- Further research into alternative treatments for SDB in PTSD patients is warranted.
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