Related Experiment Video
Updated: Jul 27, 2026

09:03
Giant Liposome Preparation for Imaging and Patch-Clamp Electrophysiology
Published on: June 21, 2013
Oil-soluble vitamins: illegal use for lip augmentation.
B Kamouna1, J Kazandjieva1, M Balabanova1
1Department of Dermatology and Venerology, Faculty of Medicine, University of Sofia, Sofia, Bulgaria.
Facial Plastic Surgery : FPS
|December 24, 2014
Summary
Unprofessional lip augmentation using vitamins A and E from capsules caused severe lip swelling and pain in six young women. These cases highlight the risks of using unapproved fillers injected by untrained individuals.
Area of Science:
- Dermatology
- Cosmetic Surgery
- Pathology
Background:
- Lip augmentation using fillers is increasingly popular in cosmetic procedures.
- Vitamins A and E, extracted from oral capsules, have been used as injectable lip fillers.
- The use of unregistered products and non-specialist injectors poses potential health risks.
Observation:
- Six young female patients presented with significant lip swelling and pain post-injection.
- Physical examination revealed firm lip indurations, tenderness, erythema, and dermal nodules.
- Histological analysis confirmed lipogranulomas with a characteristic 'Swiss cheese' appearance.
Findings:
- Injected vitamins A and/or E, extracted from oral capsules, were identified as the cause of lip granulomas.
- The procedures were performed by unprofessional physicians and beauticians in various cosmetic centers.
- Patients experienced adverse reactions including massive swellings and pain.
Implications:
- This study underscores the dangers associated with using unapproved substances as cosmetic fillers.
- It highlights the critical need for qualified practitioners and regulated products in aesthetic medicine.
- Early diagnosis and treatment with corticosteroids and antibiotics can lead to good clinical outcomes for lipogranulomas.
More Related Videos
Related Concept Videos
What are Lipids?
Overview
Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Lipid-derived Compounds in the Human Body
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Lipids: Dietary Sources and Requirements
Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

