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2-Iodoisatogens: versatile intermediates for the synthesis of nitrogen heterocycles
Elvis J M Maduli1, Steven J Edeson, Stephen Swanson
1Department of Chemistry, University of Sheffield , Sheffield S3 7HF, U.K.
Organic Letters
|December 24, 2014
Abstract:
A Cu-promoted cyclization of 2-nitrophenyl iodoacetylenes provides a direct route to a range of 2-iodoisatogens. These compounds represent useful intermediates for the late-stage elaboration of the C-I bond to furnish isatins and a range of alternative heterocyclic products.