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Updated: Apr 19, 2026

Aplysia Ganglia Preparation for Electrophysiological and Molecular Analyses of Single Neurons
Published on: January 13, 2014
Comparative analysis of early ontogeny in Bursatella leachii and Aplysia californica
Zer Vue1, Bishoy S Kamel2, Thomas R Capo3
1School of Natural Sciences, University of California , Merced, CA , USA ; Program in Developmental Biology, Baylor College of Medicine , Houston, TX , USA ; Department of Genetics, University of Texas M.D. Anderson Cancer Center , Houston, TX , USA.
Abstract:
Opisthobranch molluscs exhibit fascinating body plans associated with the evolution of shell loss in multiple lineages. Sea hares in particular are interesting because Aplysia californica is a well-studied model organism that offers a large suite of genetic tools. Bursatella leachii is a related tropical sea hare that lacks a shell as an adult and therefore lends itself to comparative analysis with A. californica. We have established an enhanced culturing procedure for B. leachii in husbandry that enabled the study of shell formation and loss in this lineage with respect to A. californica life staging.
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