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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma I: Introduction01:28

Asthma I: Introduction

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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

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Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Psychopathology in difficult asthma.

Lonneke C J Prins1, Maarten J M van Son, Anton R J van Keimpema

  • 1a Altrecht Psychosomatic Medicine , Zeist , The Netherlands .

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|December 25, 2014
PubMed
Summary
This summary is machine-generated.

Psychopathology is common in difficult asthma (DA), affecting nearly half of patients and potentially worsening exacerbations. More research is needed to understand this link in DA management.

Keywords:
Difficult asthmapsychologypsychopathology

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Area of Science:

  • Pulmonary Medicine
  • Psychiatry
  • Clinical Psychology

Background:

  • Difficult asthma (DA) is a severe asthma phenotype characterized by frequent exacerbations and healthcare utilization.
  • Psychopathology is considered in DA management, with potential bidirectional relationships: it may predispose to DA, or develop as a consequence of the condition.

Purpose of the Study:

  • To review the existing literature on empirical findings concerning psychopathology in adult patients diagnosed with difficult asthma.

Main Methods:

  • A systematic literature search was conducted using MEDLINE, Cochrane, and PsycINFO databases.
  • English-language studies published between 1990 and July 2014 were included.

Main Results:

  • The literature on psychopathology in DA is limited, with only 6 relevant articles identified out of 16 retrieved studies.
  • Nearly half of adult DA patients exhibited psychopathology at both syndrome and symptom levels.
  • Psychopathology was found to be associated with increased exacerbation frequency in DA patients.

Conclusions:

  • The review indicates a high prevalence of psychopathology among difficult asthma patients.
  • It remains uncertain if psychopathology is more prevalent in DA compared to stable asthma.
  • Further research is necessary to elucidate the role of psychopathology in the clinical presentation of DA.