Related Experiment Video
Updated: Apr 19, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Influence of microelement concentration on the intensity of alcohol withdrawal syndrome
Pedro Luis Prior1, Marta Jezierski Vaz2, Anna Carolina Ramos1
1Department of Psychobiology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Aims:
To establish a nutritional and constitutional profile concerning the micronutrient plasma concentration of patients who suffer from AWS.
Method:
Observational case control study to determine whether patients who exhibited symptoms of AWS (N = 60) had micronutrient plasmatic concentration deficiencies when compared with healthy controls (N = 34).
Results:
There were statistically significant differences between the concentrations of nutrients that are correlated with glutamate hyperactivity (zinc, magnesium and folate/vitamin B12/homocysteine).
Conclusion:
Evidence from literature and our experiment suggests that brain activity, especially the glutamatergic system, might be directly involved in micronutrient concentrations. Therefore, their supplementation to the AWS patient might improve symptom evolution.
More Related Videos
15:27Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
Published on: July 13, 2014
09:29Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Related Concept Videos
CNS Depressants: Alcohol and Nicotine
Microbes in Beverage Production
Common Ion Effect
Drug Toxicity: Dose-Dependent Reactions
Therapeutic Drug Monitoring: Affecting Factors
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...