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Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
Published on: May 26, 2013
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Viromes, not gene markers, for studying double-stranded DNA virus communities
1Department of Ecology and Evolutionary Biology, University of Arizona, Tucson Arizona, USA mbsulli@email.arizona.edu.
Journal of Virology
|December 26, 2014
Summary
Viral metagenomics offers a universal marker for studying double-stranded DNA viruses, advancing microbial ecology. This method overcomes challenges in surveying these crucial viral communities.
Area of Science:
- Microbial ecology and virology.
Background:
- Microbes are recognized as dominant natural forces.
- Viruses significantly modulate microbial communities via mortality, gene transfer, and metabolic changes.
- Community-wide virus studies lack universal markers.
Purpose of the Study:
- To propose viral metagenomics as a solution for studying double-stranded DNA viruses.
- To highlight advancements in viral metagenomics for microbial community analysis.
Main Methods:
- Utilizing viral metagenomics for comprehensive analysis.
- Surveying double-stranded DNA viruses within microbial communities.
Main Results:
- Viral metagenomics provides a universal marker for double-stranded DNA virus studies.
- Advancements enable efficient and informative surveying of these viruses.
Conclusions:
- Viral metagenomics is poised to become the primary method for studying double-stranded DNA viruses.
- This approach will enhance understanding of virus-microbe interactions in ecosystems.
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