Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.7K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.7K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

943
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
943
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

2.4K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.4K
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

68
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
68
Curing Methods01:26

Curing Methods

385
Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...
385
Drug Elimination: The Concept of Clearance01:06

Drug Elimination: The Concept of Clearance

4.5K
Drug elimination refers to removing drugs from the body, either through urine by the kidneys or through bile by the liver. Drug clearance is a pharmacokinetic parameter that measures the efficiency of drug removal from the bloodstream within a specific time frame. It is calculated as the rate at which a drug is eliminated from plasma divided by the plasma concentration of the drug.
Drug clearance is not limited to renal excretion but encompasses all organs involved in drug elimination,...
4.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness and tolerability of pharmacological prophylaxis for migraine headaches: a systematic review and network meta-analysis of randomised controlled trials.

BMJ evidence-based medicine·2026
Same author

Effectiveness and Tolerability of Pharmacologic Prophylaxis for Chronic Migraine : A Systematic Review of Randomized Controlled Trials.

Annals of internal medicine·2026
Same author

Nevus lipomatosus cutaneous superficialis presenting as a coalescent gluteal plaque.

BMJ case reports·2026
Same author

Effectiveness and tolerability of pharmacological prophylaxis in migraine patients with prior preventive treatment failure: A systematic review and network meta-analysis of randomized controlled trials.

Cephalalgia : an international journal of headache·2026
Same author

Cutaneous infections and infestations.

Clinical and experimental dermatology·2026
Same author

Nature's Bandage: A Memorable Rescue of Severe Pemphigus Vulgaris in a Resource-Limited Setting.

Clinical and experimental dermatology·2026
Same journal

Erratum: A case of anterior cerebral artery A1 segment hypoplasia syndrome presenting with right lower limb monoplegia, abulia, and urinary incontinence.

Journal of neurosciences in rural practice·2024
Same journal

An inexpensive foramen magnum decompression training tool: Feasibility and validation study.

Journal of neurosciences in rural practice·2024
Same journal

Pitching for the hitch: Neodural tenting sutures to prevent post-cranioplasty collection in a sunken craniectomy site.

Journal of neurosciences in rural practice·2024
Same journal

Importance of <sup>1</sup>H-MR spectroscopy of the brain to identify the minimal hepatic encephalopathy in different patients with liver cirrhosis: A prospective study.

Journal of neurosciences in rural practice·2024
Same journal

Lateral sacral artery aneurysm.

Journal of neurosciences in rural practice·2024
Same journal

Comparing distributed versus massed practice on functional recovery and Brain-Derived Neurotrophic Factor (BDNF) in acute stroke subjects.

Journal of neurosciences in rural practice·2024
See all related articles

Related Experiment Video

Updated: Apr 19, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

15.7K

Leprosy elimination: A myth busted.

Nidhi Yadav1, Sumit Kar1, Bhushan Madke1

  • 1Department of Dermatology, Venereology, Leprosy, Mahatma Gandhi Institute of Medical Sciences, Wardha, Maharashtra, India.

Journal of Neurosciences in Rural Practice
|December 26, 2014
PubMed
Summary
This summary is machine-generated.

Leprosy remains a concern in India, with a study finding significant nerve involvement and deformities in new cases. Active surveillance is crucial for detecting undetected leprosy infections.

Keywords:
Deformityeliminationsubclinical cases

More Related Videos

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA

Published on: July 15, 2011

27.9K
A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
12:22

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

23.1K

Related Experiment Videos

Last Updated: Apr 19, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

15.7K
DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA

Published on: July 15, 2011

27.9K
A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line
12:22

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

23.1K

Area of Science:

  • Medical Research
  • Epidemiology
  • Dermatology

Background:

  • Leprosy, a chronic infectious disease caused by Mycobacterium leprae, primarily affects the skin and peripheral nerves.
  • Despite national elimination targets achieved in 2006, India continues to report a substantial proportion of global leprosy cases.
  • The disease poses ongoing public health challenges, necessitating continued vigilance.

Purpose of the Study:

  • To investigate the clinical and epidemiological characteristics of newly diagnosed leprosy patients.
  • To understand the disease patterns in a rural tertiary healthcare setting.

Main Methods:

  • A study involving 35 newly diagnosed leprosy cases between September 2012 and August 2013.
  • Data collection included detailed patient history, assessment of deformities and sensory loss, slit skin smear for Acid-Fast Bacilli (AFB), and histopathological examination.

Main Results:

  • The highest incidence of new leprosy cases was observed in the 20-39 and 40-59 age groups, with males constituting the majority (68.57%).
  • Facial deformity, particularly earlobe thickening, was present in 48.57% of cases. Ulnar nerve involvement was most common (88.87%).
  • Slit skin smears were positive in 27/35 patients, and histopathology revealed various forms, including lepromatous (28.57%) and tuberculoid (17.14%) types.

Conclusions:

  • Leprosy elimination has not yet been fully achieved, underscoring the need for ongoing efforts.
  • Active surveillance is essential for identifying subclinical and undiagnosed leprosy cases to prevent further transmission and complications.