Related Experiment Video
Updated: Apr 19, 2026
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Systemic sclerosis and occupational exposures: About a case in a driller-powderman]
M Boulanger1, B Bienvenu2, M-F Marquignon1
1Service de santé au travail et pathologie professionnelle, CHU Côte-de-Nacre, 14033 Caen cedex, France; Institut de recherche et de formation en santé au travail de Basse-Normandie, faculté de médecine de Caen, 14033 Caen cedex, France.
Introduction:
Erasmus' syndrome is the association between systemic sclerosis and silica exposure.
Case Report:
We report a case of this syndrome in a driller-powderman exposed to silica and nitro compounds contained in explosives.
Conclusion:
Physiopathology and etiologies of systemic sclerosis are still not well known. However, nitric oxide, a product of nitro compounds metabolism, is involved in the physiopathology of the disease: it seems thus licit to wonder about the consequences of an uncontrolled occupational exposure to nitric oxide on the vascular function, already damaged by systemic sclerosis. To a wider extent, our report highlights the importance of a comprehensive and detailed collection of occupational exposures for patients diagnosed with systemic sclerosis.
