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Updated: Apr 19, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
Whole mitochondrial genome sequencing and analysis for chronic obstructive pulmonary disease rat strain
Zhi-Ming Jiang1, Qing-Sheng Zhao2, Yong-Qing Xu1
1a Department of Critical-care Medicine , Qianfoshan Hospital affiliated to Shandong University , Jinan , China and.
Abstract:
Mitochondrial genome plays a central role in aging, cancer, apoptosis and metabolism. We sequenced a complete mitochondrial genome sequence of a rat chronic obstructive pulmonary disease rat strain for the first time. The total length of the mitochondrial genome was 16,310 bp and coding 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes. This genome describing information will supply the potential use of mtDNA mutations as markers in cancer.
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