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Updated: Apr 19, 2026

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
Published on: March 17, 2023
Whole mitochondrial genome sequencing and analysis for rat squamous cell carcinoma tissue cell
Ya-Kun Gao1, Xiao-Lin Xu1, Feng Miao1
1a Department of Cardiothoracic , Affiliated Huashan Hospital of Fudan University , Shanghai , China.
Abstract:
Mitochondrial genome plays a central role in aging, cancer, apoptosis and metabolism. Squamous cell carcinoma is one of the major types of non-small cell lung cancer. We sequenced a complete mitochondrial genome sequence of a rat squamous cell carcinomas cell tissue for the first time. The total length of the mitochondrial genome was 16,319 bp, with 13 protein-coding genes, two ribosomal RNA genes and 22 transfer RNA genes. This genome describing information will supply the potential use of mtDNA mutations as markers in cancer.

