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Updated: Apr 19, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
[Course and neurological/behavioral development of preterm children]
S Marret1, C Chollat1, R de Quelen1
1Service de pédiatrie néonatale et réanimation, centre d'éducation fonctionnelle, centre de référence des troubles des apprentissages de l'enfant, hôpital Charles-Nicolle, CHU de Rouen, Rouen, France; Équipe Inserm région (ERI28), handicap périnatal, institut de recherche et d'innovation biomédicale, faculté de médecine et de pharmacie, université de Rouen, Rouen, France.
Insights
Preterm birth affects 1 in 10 infants. While survival improves, cognitive disabilities persist, impacting school readiness and necessitating early detection and interventions for better neurodevelopmental outcomes.
Area of Science:
- Neonatal Medicine
- Developmental Pediatrics
- Public Health
Context:
- Preterm birth is a significant global health concern, with 1 in 10 infants born before 37 weeks gestation.
- Survival rates for extremely preterm infants (before 27 weeks) have improved in high-income nations like France.
- While severe handicaps like cerebral palsy may be decreasing, cognitive disabilities remain common.
Purpose:
- To highlight the persistent challenge of cognitive disabilities in preterm infants, despite improved survival rates.
- To emphasize the link between decreased gestational age and increased prevalence of sequelae.
- To advocate for better characterization of neurodevelopment in recent preterm cohorts to enable early detection and intervention.
Summary:
- Despite advances in neonatal care, preterm birth (before 37 weeks) continues to affect a substantial proportion of infants.
- Cognitive and neurological disabilities are frequent sequelae, impacting learning and leading to special education needs.
- The number of children with disabilities is similar in very preterm and moderate/late preterm groups due to population size.
Impact:
- Improved understanding of neurodevelopmental variations in preterm infants can lead to earlier identification of learning challenges.
- Targeted remediation strategies focusing on areas like working memory and language may reduce the incidence of learning disabilities.
- This research supports the development of evidence-based interventions to improve long-term academic and developmental outcomes for children born preterm.
Abstract:
Preterm birth remains a public health priority given that one child out of ten is born before 37 weeks of gestation. Survival without major neonatal morbidity has increased in high-income countries, in particular in France and in cases of extreme preterm birth before 27 weeks of gestation. Rate of severe handicaps, such as cerebral palsy, is probably decreasing, but specific cognitive disabilities in a variety of domains remain frequent, interfering with normal learning abilities at school and explaining the high rate of special education needs. Prevalence of sequelae increases when gestational age at birth decreases. However, because there are more moderate to late preterm children compared to very preterm children, the absolute number of children with specific cognitive or neurological disabilities is equivalent in these two groups. Better characterization of the development in a recent cohort of very preterm children is necessary to improve the early detection of variations in normal neurodevelopment and to propose trials with remediation actions targeting working memory and language for example. These protocols could decrease the rates of learning disabilities at school.
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