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Updated: Apr 19, 2026

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Published on: June 11, 2019
Left main coronary artery thrombosis revealing angio-Behçet syndrome
Jihen Ayari1, Mohamed S Mourali1, Abdjalil Farhati1
1Department of Cardiological Investigations and Resuscitation, La Rabta University Hospital, Tunis, Tunisia.
Insights
Young adults experiencing myocardial infarction may have rare causes like Behçet's disease, not just atherosclerosis. This case highlights the importance of considering unusual etiologies in myocardial infarction diagnosis.
Area of Science:
- Cardiology
- Rheumatology
- Vascular Medicine
Background:
- Acute myocardial infarction (AMI) is typically caused by coronary atherothrombosis.
- However, alternative etiologies must be considered in young adults lacking traditional atherosclerotic risk factors.
- Thrombophilia and coronary arteritis are potential, less common causes of AMI.
Purpose of the Study:
- To present a case of myocardial infarction in a young adult attributed to Behçet's disease.
- To emphasize the diagnostic considerations for non-atherosclerotic causes of coronary artery thrombosis.
Main Methods:
- Case report presentation.
- Review of clinical presentation, diagnostic workup, and treatment.
- Literature review on Behçet's disease and arterial involvement.
Main Results:
- A 38-year-old male without prior medical history presented with myocardial infarction.
- Diagnosis revealed thrombosis of the left main coronary artery.
- The underlying cause was identified as Behçet's disease with arterial involvement.
Conclusions:
- Behçet's disease can manifest as coronary artery thrombosis leading to myocardial infarction in young individuals.
- Diagnostic vigilance for inflammatory and thrombophilic conditions is crucial in young AMI patients.
- Early recognition and management of Behçet's disease are vital to prevent recurrent cardiovascular events.
Abstract:
Although acute myocardial infarction commonly results from coronary atherothrombosis, there are several other etiologies that should be taken initially into account, especially in young adults without significant atherosclerotic risk factors. Thrombophilia and coronary arteritis are, in this context, examples of etiologies that should be looked after. Through this article, we present a case of Behçet's disease with arterial involvement diagnosed after myocardial infarction resulting from thrombosis of the left main coronary artery in a 38-year-old young man without any particular past medical history.
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