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Dechlorane Plus in paired hair and serum samples from e-waste workers: correlation and differences
Kehui Chen1, Jing Zheng2, Xiao Yan3
1State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
Chemosphere
|December 28, 2014
Summary
Human hair and serum analysis reveals Dechlorane Plus (DP) exposure in e-waste workers. Hair is a viable biomonitoring tool, showing significant correlations with serum DP levels, but isomer composition differs, suggesting selective bioaccumulation.
Area of Science:
- Environmental Science
- Toxicology
- Human Biomonitoring
Background:
- Dechlorane Plus (DP) is a flame retardant with potential environmental and health concerns.
- E-waste recycling sites are recognized sources of persistent organic pollutants.
Purpose of the Study:
- To assess Dechlorane Plus (DP) exposure levels in e-waste recycling workers in South China.
- To investigate the correlation between DP concentrations in human hair and serum.
- To explore potential gender-specific differences in DP accumulation.
Main Methods:
- Analysis of Dechlorane Plus (DP) and its dechlorinated product in matched human hair and serum samples.
- Quantification using gas chromatography-mass spectrometry (GC-MS).
- Statistical analysis to determine correlations and gender differences.
Main Results:
- Significant positive correlations were observed between DP concentrations in hair and serum.
- DP isomer composition differed between hair and serum, indicating stereoselective bioaccumulation.
- A notable gender difference in DP levels was found in hair samples, with correlations to serum levels differing between males and females.
Conclusions:
- Human hair serves as a suitable matrix for monitoring Dechlorane Plus (DP) exposure.
- Stereoselective bioaccumulation of DP occurs during its absorption into hair.
- Gender influences DP accumulation and its correlation between hair and serum, potentially due to differences in hair exposure time.
