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Updated: Apr 19, 2026

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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
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Chorionic bump on first-trimester sonography: not necessarily a poor prognostic indicator for pregnancy
Elizabeth Kagan Arleo1, Robert N Troiano2
1New York-Presbyterian/Weill Cornell Hospital, New York, New York USA. ela9033@med.cornelledu.
Summary
A chorionic bump in early pregnancy has a 65% live birth rate overall. If the pregnancy is otherwise normal, the live birth rate for chorionic bumps increases to 83%.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Diagnostic Ultrasound
Background:
- A chorionic bump is a bulge from the choriodecidual surface into the gestational sac.
- Its impact on pregnancy outcomes is not fully understood.
Purpose of the Study:
- To determine the live birth rate in pregnancies diagnosed with a chorionic bump during the first trimester.
Main Methods:
- Prospective observational study of pregnant patients aged 18+ with a first-trimester chorionic bump.
- Assessed chorionic bump size, number, and history of infertility or coagulation disorders.
- Primary endpoint was pregnancy outcome.
Main Results:
- 52 pregnancies with a chorionic bump yielded a 65% live birth rate (34/52).
- In otherwise normal pregnancies (n=41), the live birth rate was 83% (34/41).
- Multiple chorionic bumps (4) resulted in 100% demise; size and outcome showed no significant correlation.
Conclusions:
- A chorionic bump diagnosis in the first trimester has a 65% overall live birth rate.
- The prognosis is more favorable (83% live birth rate) in otherwise normal pregnancies.
- A chorionic bump does not necessarily indicate a poor pregnancy prognosis.
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