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Technetium-pertechnetate uptake by ectopic antral mucosa. An experimental study.

D Parekh, H H Lawson, J Esser

South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie

|September 1, 1989

Summary

Ectopic antral mucosa can concentrate technetium, though less effectively than stomach fundic mucosa. This finding suggests technetium scanning may aid in detecting misplaced or retained antral tissue.

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Area of Science:

Gastroenterology
Nuclear Medicine
Surgical Research

Background:

Ectopic fundic mucosa and retained antral mucosa are known to concentrate technetium.
The technetium-concentrating ability of ectopic antral mucosa has not been previously established.

Purpose of the Study:

To investigate the capacity of denervated ectopic antral mucosa, when implanted into the colon, to concentrate technetium.
To compare the technetium uptake of ectopic antral mucosa with that of native stomach fundic mucosa.

Main Methods:

Surgical implantation of denervated antral segments into the colons of 5 dogs.
Administration of technetium and subsequent scanning to assess tissue uptake.

Main Results:

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The denervated antrum implanted into the colon demonstrated technetium concentration.

This concentration was significantly lower (P < 0.005) compared to parietal cell-containing fundic mucosa of the stomach.

Conclusions:

Ectopic antral mucosa exhibits a capacity for technetium concentration.
Technetium scanning shows potential utility in identifying ectopic and retained antral mucosa.