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Is the Epstein-Barr virus involved in Hodgkin's disease?
M Boiocchi1, A Carbone, V De Re
1Division of Experimental Oncology 1, Aviano, Italy.
Tumori
|August 31, 1989
Abstract:
EBV genomes, in clonal episomal form, were detected in 7 out of 17 cases of Hodgkin's disease (HD) and in a single case of non-Hodgkin's lymphoma which occurred in a patient after therapeutic treatment for HD. The experimental data presented imply that a clonal cell population, harboring the EBV genome, must be present in EBV-positive HD. In light of this finding we are attempting to reconsider the abundant literature on this lymphoproliferative disorder, and suggest a reevaluation of the possibility that EBV could be etiologically involved in HD.