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Updated: Apr 19, 2026
Electric and Magnetic Field Devices for Stimulation of Biological Tissues
Published on: May 15, 2021
Effects of a continuous electromagnetic field on wound healing in human airway
Dong-Hyun Kim1, Hyun Jun Kim2, Yoon-Myoung Gimm3
1Department of Otolaryngology-Head and Neck Surgery, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul.
Objectives/Hypothesis:
The aim of this study was to investigate the effect of a 1.8-GHz continuous electromagnetic field (EMF) on wound healing in a human airway cell-culture system.
Study Design:
In vitro study using a cell line.
Methods:
Immortalized human bronchial epithelial cells (a BEAS-2B cell line) were exposed to a 1.8-GHz EMF (specific absorption rate = 1.0 W/kg). We evaluated the effect of EMF on the cells using an 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) viability assay, by cell counting, and by using fluorescence-activated cell sorting (FACS) analysis of cell cycle dynamics and apoptosis. Inhibition of migration was tested by a wound-healing assay on scratched cell cultures.
Results:
Cell migration in the wound-healing assay was decreased by the EMF treatment compared with controls. The MTT assay and cell counting consistently showed that the EMF used was not cytotoxic and did not inhibit cell proliferation. FACS analysis showed no alterations in the cell-cycle phase distribution or in apoptosis after EMF exposure.
Conclusion:
EMF can inhibit wound healing in vitro by inhibiting cell migration.
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