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Related Experiment Video

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Ocular surface sensitivity repeatability with Cochet-Bonnet esthesiometer.

Cecilia Chao1, Fiona Stapleton, Ezailina Badarudin

  • 1*MOptom †PhD, FAAO ‡MSc §PhD School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia (all authors).

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|December 30, 2014
PubMed
Summary
This summary is machine-generated.

Ocular surface threshold measurements using the Cochet-Bonnet esthesiometer show good repeatability for the central cornea, both on the same day and after 3 months. However, this device is not recommended for conjunctival threshold measurements due to poor repeatability.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Biomedical Engineering

Background:

  • Ocular surface sensitivity is crucial for diagnosing conditions like dry eye disease.
  • The Cochet-Bonnet esthesiometer is a common tool for measuring corneal sensitivity.
  • Understanding the repeatability of this device is essential for reliable clinical assessment.

Purpose of the Study:

  • To evaluate the repeatability of ocular surface threshold measurements using the Cochet-Bonnet esthesiometer.
  • To assess repeatability on the same day and after a 3-month interval.
  • To compare repeatability between corneal and conjunctival measurements.

Main Methods:

  • Two studies were conducted to assess repeatability: same-day (n=20) and 3-month interval (n=29).
  • Corneal and inferior conjunctival thresholds were measured using the Cochet-Bonnet esthesiometer and the ascending method of limits.
  • Device calibration using an analytical balance determined pressure from filament length, and Bland-Altman analysis assessed repeatability.

Main Results:

  • The Cochet-Bonnet esthesiometer's actual pressure output differed from manufacturer specifications and varied by filament diameter.
  • Repeatability of central corneal threshold measurements was good, with better results for same-day measurements (CoR = ±0.23 g/mm²) than 3-month measurements (CoR = ±0.52 g/mm²).
  • Inferior conjunctival threshold measurements demonstrated poor repeatability (CoR = ±12.78 g/mm²).

Conclusions:

  • Cochet-Bonnet esthesiometry demonstrates good repeatability for central corneal threshold measurements.
  • The instrument is suitable for assessing corneal sensitivity both acutely and over a 3-month period.
  • The Cochet-Bonnet esthesiometer is not recommended for measuring conjunctival sensitivity due to insufficient repeatability.