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Cost-utility analyses of cognitive-behavioural therapy of depression: a systematic review

Christian Brettschneider1, Helei Djadran, Martin Härter

  • 1Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Psychotherapy and Psychosomatics
|December 31, 2014
PubMed

Insights

Cognitive Behavioural Therapy (CBT) is a cost-effective treatment for major depressive disorder (MDD) in adults for short-term care and relapse prevention. This systematic review analyzed cost-utility analyses of CBT for MDD.

Area of Science:

  • Health Economics
  • Psychiatry
  • Evidence-Based Medicine

Background:

  • Major Depressive Disorder (MDD) presents a significant global health burden.
  • Cognitive Behavioural Therapy (CBT) is a key intervention for depression.
  • Cost-Utility Analysis (CUA) informs resource allocation in health policy.

Purpose of the Study:

  • To systematically review CUAs of CBT for MDD treatment.
  • To assess the economic value of CBT interventions for depression.

Main Methods:

  • Systematic literature search across major databases (Medline, Embase, PsycINFO, NHS EED).
  • Standardized cost data adjustment (year 2011, USD PPP).
  • Quality assessment of included CUAs.

Main Results:

  • Twenty-two studies were included in the review.
  • Individual, group, and maintenance CBT generally showed acceptable cost-utility ratios (<50,000 USD PPP/QALY).
  • CUA results for pediatric and computerized CBT were inconsistent.

Conclusions:

  • Consistent evidence supports individualized CBT as cost-effective for short-term MDD treatment and relapse prevention in adults.
  • Findings are from a third-party payer perspective.
  • Short time horizons (<5 years) were common across studies.
Abstract

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