Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infections as contributing factors to atopic dermatitis.

I Rystedt1, I L Strannegård, O Strannegård

  • 1Dept. of Occupational Dermatology, National Board of Occupational Health, Stockholm, Sweden.

Allergy
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incidence and pathogenesis of clinical relapse after herpes simplex encephalitis in adults.

Journal of neurology·2005
Same author

Asthma hospitalizations continue to decrease in schoolchildren but hospitalization rates for wheezing illnesses remain high in young children.

Acta paediatrica (Oslo, Norway : 1992)·2002
Same author

Early sensitisation to food antigens--when and how?

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2001
Same author

The causes of the increasing prevalence of allergy: is atopy a microbial deprivation disorder?

Allergy·2001
Same author

Allergy and neonatal care.

Allergy·2000
Same author

Topical steroid treatment of allergic rhinitis decreases nasal fluid TH2 cytokines, eosinophils, eosinophil cationic protein, and IgE but has no significant effect on IFN-gamma, IL-1beta, TNF-alpha, or neutrophils.

The Journal of allergy and clinical immunology·2000
Same journal

Decoding the "Metallic" Immune Imprint: Single-Cell Exposomics Reveals the Immune Imprint of Fire Smoke.

Allergy·2026
Same journal

Immunonutrition in Early Life: The Role of Complementary Feeding, Dietary Patterns, and Nutritional Exposures on the Health of Young Children-An EAACI Scoping Review.

Allergy·2026
Same journal

Detergent-Containing Toothpaste Decreases Esophageal Mucosal Impedance and Alters Salivary Properties in Humans.

Allergy·2026
Same journal

Global Variation in Timing of Allergenic Food Introduction for Food Allergy Prevention: An International Survey of Healthcare Professionals.

Allergy·2026
Same journal

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma.

Allergy·2026
Same journal

Surgical Management of Non-Allergic Rhinitis-An EAACI Task Force Position Paper.

Allergy·2026
See all related articles

Patients with atopic dermatitis (AD) experience more severe viral skin infections due to immune dysfunction. While infections are common in AD, they are likely a consequence, not a cause, of the condition.

Area of Science:

  • Dermatology
  • Immunology
  • Infectious Diseases

Background:

  • Atopic dermatitis (AD) is frequently associated with cutaneous viral infections.
  • Patients with AD show increased susceptibility to severe Herpes simplex, vaccinia, and varicella infections.
  • Skin colonization with staphylococci and streptococci is common in AD patients.

Purpose of the Study:

  • To investigate the relationship between infections and atopic dermatitis.
  • To understand the role of immune dysfunction in increased infection severity in AD.
  • To determine if infections cause or are a consequence of AD.

Main Methods:

  • Review of clinical observations and immunological data in AD patients.
  • Analysis of infection frequencies and severity in relation to AD.

Related Experiment Videos

  • Evaluation of antibody titers and skin microbiota.

    • Main Results:

    • AD patients exhibit higher frequencies of recurrent cold sores and Herpes zoster.
    • Elevated antibody titers to Epstein-Barr virus are observed in AD patients.
    • Dysfunctional cell-mediated immunity and skin changes in AD contribute to infection susceptibility.

    Conclusions:

    • Infections in AD are likely a consequence of the disease, not a primary cause.
    • Immune dysregulation and skin barrier defects in AD predispose individuals to severe infections.
    • Further research is needed to confirm the causal role of infections in AD exacerbation.