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Detecting Behavioral Deficits in Rats After Traumatic Brain Injury
Published on: January 30, 2018
Validity of an adapted scoring method for a Modified Six Elements Test in individuals with brain injury
Dirk Bertens1, Nikita Frankenmolen2, Danielle H E Boelen3
1Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen 6500 HE, The Netherlands d.bertens@donders.ru.nl dirkbertens.np@gmail.com.
Abstract:
The Modified Six Elements Test (MSET) assesses several executive functions. We examined whether an adapted scoring method is appropriate for discriminating between brain-injured persons with and without executive deficits. A MSET was administered to 70 participants with acquired brain injury in the chronic phase. The group was divided into individuals with and without executive impairments based on several other executive tests. The discriminative value for both the conventional raw score and the adapted scoring method was evaluated using receiver operating characteristic analyses. Both scoring methods discriminated significantly between persons with impaired and unimpaired executive functions (raw score: area under the curve, AUC = 0.703, p = .004; adapted score: AUC = 0.780, p = .000). Only the adapted scoring method proved sensitive (81%) and specific (67%) within a clinically useful range. Within this range, an acceptable cut-off score could be determined. Altogether, the proposed MSET scoring index is a potentially clinically useful contribution to the measurement of executive functions.

