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Updated: Apr 19, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Sphenoid sinus agenesis].
Serdar Baylançiçek1, Mehmet Erdem Yıldız, Mehmet Emre Üstündağ
1Department of Otolaryngology, Acıbadem Healthcare Group, Kozyatağı Acıbadem Hospital, 34742 Kozyatağı, İstanbul, Turkey. baylancicek@yahoo.com.
Agenesis of paranasal sinuses, particularly sphenoid sinus agenesis, is extremely rare. This case highlights an 18-year-old female with absent sphenoid sinuses, emphasizing the need for surgical awareness.
Area of Science:
- Radiology
- Otolaryngology
- Anatomy
Background:
- Paranasal sinus agenesis is uncommon, typically affecting frontal and maxillary sinuses.
- Agenesis of the sphenoid sinuses is exceptionally rare in clinical practice.
Observation:
- An 18-year-old female presented with headache and nasal obstruction.
- Imaging revealed congenital absence of the sphenoid sinuses without other cranial or skeletal abnormalities.
Findings:
- Computed tomography confirmed bilateral sphenoid sinus agenesis.
- This rare condition presents without typical associated anomalies.
Implications:
- Surgeons must consider sphenoid sinus agenesis in surgical planning.
- Awareness is crucial for procedures like transsphenoidal hypophysectomy and endoscopic sinus surgery.
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