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Recombinant human interferon alpha-2b enhances the radiosensitivity of small cell lung cancer in vitro
D Kardamakis1, N E Gillies, R L Souhami
1Imperial Cancer Research Fund, University College, London, England.
Anticancer Research
|July 1, 1989
Abstract:
We have studied the effects of human recombinant interferon alpha on the radiobiological response and the cell cycle distribution of human small cell lung cancer cell lines. In two small cell lung cancer cell lines tested so far, pretreatment with interferon alpha was found to increase the radiation sensitivity without altering the distribution of cells in the cell cycle.