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[Cannabinoid hyperemesis syndrome: about 6 cases].

J Bertolino1, L Abdo2, D Khau3

  • 1Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France; Université d'Aix-Marseille , 13284 Marseille, France.

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PubMed
Summary

Cannabinoid hyperemesis syndrome (CHS), marked by cyclic nausea and vomiting relieved by hot showers, affects young adults using cannabis long-term. Definitive cannabis cessation is the primary treatment for symptom resolution.

Keywords:
Cannabinoid hyperemesis syndromeCannabisDouches chaudesHot showersSyndrome d’hyperémèse cannabiqueVomissementVomiting

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Area of Science:

  • Gastroenterology
  • Toxicology
  • Addiction Medicine

Background:

  • Cannabinoid hyperemesis syndrome (CHS) is a condition causing cyclical nausea, vomiting, and abdominal pain in chronic, long-term cannabis users.
  • A hallmark of CHS is the paradoxical relief of symptoms through hot showers.

Observation:

  • Six cases of CHS are presented, involving three men and three women, all chronic cannabis consumers.
  • Patients experienced nausea, vomiting, abdominal pain (worse in the morning), and weight loss, with symptom improvement after hot showers.
  • Standard medical investigations were inconclusive, delaying diagnosis.

Findings:

  • CHS diagnosis is primarily clinical, based on characteristic symptoms and response to hot bathing.
  • Undiagnosed CHS leads to extensive, costly, and potentially invasive medical evaluations.
  • The underlying pathophysiology of CHS remains unclear.

Implications:

  • Early clinical recognition of CHS is crucial to prevent unnecessary medical interventions.
  • Definitive cessation of cannabis use is the cornerstone of effective CHS management.
  • Further research into CHS pathophysiology is needed to guide targeted therapeutic strategies.