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Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
Published on: February 16, 2018
Molecularly imprinted sol-gel materials for medical applications
Riccardo Concu, Mariana Ornelas, Manuel Azenha1
1Centro de Investigacao em Quimica - CIQUP, Faculty of Science, University of Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal. mazenha@fc.up.pt.
Abstract:
The present review deals with the sol-gel imprinting of both drug and non-drug templates of medical relevance, namely neurotransmitters, biomarkers, hormones, proteins and cells. Nearly a hundred recent works, either developmental or applied in a medical-related context, were critically analyzed. It may be concluded that, although research is still at an early stage, the potential of these sol-gel materials was well demonstrated in a few applications of critical interest for medicinal/biomedical science. The vast room left for expansion and improvement envisages a continuously growing interest by researchers in the future, eventually resulting in important medical applications able to enter the professional and consumer medical markets.

