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Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti ratti Infection
Published on: January 17, 2025
Five cases of recurrent meningitis associated with chronic strongyloidiasis
Teppei Shimasaki1, Heath Chung2, Soichi Shiiki2
1Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii; Department of Medicine, Okinawa Chubu Hospital, Okinawa, Japan shimasaki.t@gmail.com.
Abstract:
Although meningitis secondary to chronic strongyloidiasis is a rare complication, it is associated with a high mortality rate. Recurrent meningitis can occur if the underlying parasitic infection is left untreated. We report five cases of recurrent meningitis related to chronic strongyloidiasis that were associated with human T-lymphotropic virus type 1 (HTLV-1) infection. Common causative organisms are Escherichia coli, Streptococcus bovis, and Klebsiella pneumonia. One patient died during the second episode of meningitis. Three patients showed significant gastrointestinal and respiratory symptoms before developing headache and fever. In four cases, patients developed multiple recurrences even with the treatment of thiabendazol. Ivermectin seems to be a better agent compared with thiabendazol to achieve eradication of strongyloidiasis.
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