Related Experiment Video
Updated: Apr 19, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
Surgical management of extensive peristomal pyoderma gangrenosum associated with colon cancer
Kosuke Ishikawa1, Toshiyuki Minamimoto, Takeo Mizuki
1Kosuke Ishikawa, MD Department of Plastic and Reconstructive Surgery, Hakodaate Municipal Hospital, Hakodate, Japan. Toshiyuki Minamimoto, MD, PhD, Department of Plastic and Reconstructive Surgery, Hakodate Municipal Hospital, Hakodate, Japan. Takeo Mizuki, RN, WOCN, Department of Nursing Care, Hakodate Municipal Hospital, Hakodate, Japan. Hiroshi Furukawa, MD, PhD, Department of Plastic and Reconstructive Surgery, Hokkaido University Graduate School of Medicine, Hakodate, Japan.
Background:
Extensive peristomal skin ulcer due to pyoderma gangrenosum is difficult to manage and causes significant morbidity.
Case:
A 69-year-old man presented with a 10×7-cm painful peristomal skin necrosis during cancer chemotherapy for metastatic colon adenocarcinoma. The diagnosis of peristomal pyoderma gangrenosum was made on the basis of the presence of the skin necrosis with a well-defined, undermined, violaceous border. One month after the presentation along with daily cleansing and minimal debridement without immunosuppressive treatments, wound bed preparation was deemed sufficient for a split-thickness skin graft using negative pressure wound therapy for graft fixation. One month after the operation, the ulcer was completely healed and the patient could manage ostomy pouching independently. He died of cancer 5 months later; no recurrence of the ulcer was observed during this period.
Conclusion:
Peristomal pyoderma gangrenosum was successfully treated with skin grafting after local wound management. Negative pressure wound therapy was useful for skin graft fixation in the peristomal region.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
