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Published on: January 17, 2013
[Imaging characteristics of basilar artery hypoplasia]
Hua Gu1, Xiaojun Qian1, Shuangkun Wang1
1Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Insights
Basilar artery hypoplasia (BAH) is a rare vascular condition, more prevalent in females. It often co-occurs with fetal-type posterior circulation and vertebral artery hypoplasia, and is linked to acute cerebral infarction.
Area of Science:
- Neurology
- Radiology
- Vascular Imaging
Background:
- Basilar artery hypoplasia (BAH) is a rare vascular abnormality.
- Understanding its imaging characteristics is crucial for diagnosis and management.
Purpose of the Study:
- To determine the imaging characteristics of basilar artery hypoplasia (BAH).
Main Methods:
- Retrospective analysis of 10,193 MRA and 31,716 MRI cases.
- BAH defined as basilar artery diameter ≤ 2 mm.
- Assessment of associated vertebral artery hypoplasia (VAH) and fetal-type posterior circle of Willis (FTP).
Main Results:
- 210 cases of BAH identified (2.06% prevalence).
- BAH more common in females (56.7%); associated with FTP (83.3% bilateral) and VAH (99.5% V4, 56.0% V1-V3).
- 74 BAH patients (35.2%) had acute cerebral infarction (ACI), with males predominant in ACI cases.
Conclusions:
- BAH is a rare vascular abnormality.
- BAH is consistently associated with unilateral or bilateral FTP and V4 VAH.
- BAH may be a risk factor for acute cerebral infarction, particularly in males.
Objective:
To determine the imaging characteristics of basilar artery hypoplasia (BAH).
Methods:
From October 2009 to August 2013, 10 193 magnetic resonance angiogram (MRA) and 31 716 magnetic resonance imaging (MRI) consecutive cases were retrospectively retrieved from our institutional Picture Archiving and Communication System (PACS) database. BAH was defined as a continuous diameter reduction all over artery and a basilar artery diameter ≤ 2 mm. The same cut-off value was applied for vertebral artery hypoplasia (VAH). We measured the diameters of basilar and vertebral arteries with PACS in all patients according to source imaging and IMP construction of MRA. The carotid arterial computed tomography angiogram (CTA) profiles were reviewed in 50 patients. The fetal-type posterior circle of Willis (FTP) was assessed. The diagnosis of acute cerebral infarction was based on clinical symptoms, signs and a high signal on diffusion-weighted imaging (DWI). Acute cerebral infarction was divided into anterior circulation stroke (ACS) and posterior circulation stroke (PCS).
Results:
A total of 210 BAH were identified among 10 193 consecutive patients. BAH was more common in females (56.7%) than males (43.3%) in the patient group. They had a fetal-type of posterior cerebral artery (FTP) (175 bilateral (83.3%), 35 unilateral (16.7%)). 99.5% patients had V4 VAH and 56.0% (28/50) V1-V3 VAH. Among 210 BAH, there are 74 patients (mean age 64 years, average 25-91 years, 44 males) with a diagnosis of acute cerebral infarction (ACI). The males were predominant in ACI (59.5% in males vs 40.5% in females, P = 0.021). The frequency of BAH was detected in 74 (2.2%) among 3 294 ACI patients.
Conclusion:
As a relatively rare vascular abnormality, BAH has always unilateral or bilateral FTP and V4 VAH.
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