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Anterior Cervical Discectomy and Fusion in the Ovine Model
Published on: October 5, 2009
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Anterior cervical disc replacement for degenerative disc disease
Sudarshan Munigangaiah1, John P McCabe
1Spine Service, Department of Trauma and Orthopaedic Surgery, Galway University Hospitals, Newcastle Road, Galway, Ireland.
Journal of Orthopaedic Surgery (Hong Kong)
|January 1, 2015
Summary
Anterior cervical disc replacement using the Prestige LP system significantly improved patient outcomes for degenerative disc disease. The implant demonstrated safety and effectiveness in one- and two-level procedures.
Area of Science:
- Spine surgery
- Orthopedics
- Neurosurgery
Background:
- Degenerative disc disease is a common cause of neck and arm pain.
- Anterior cervical disc replacement (ACDR) aims to preserve motion at the operated level.
- The Prestige LP system is an implant used for ACDR.
Purpose of the Study:
- To evaluate the clinical outcomes of ACDR using the Prestige LP system.
- To assess the safety and efficacy of the Prestige LP implant for degenerative disc disease.
Main Methods:
- Retrospective review of 48 ACDR procedures in 35 patients (12 men, 23 women) aged 26-66.
- Procedures included one-level (C5-C6, C6-C7) and two-level (C5-C6/C6-C7, C4-C5/C5-C6, C6-C7/C7-T1) replacements.
- Outcomes measured included Neck Disability Index (NDI), Visual Analogue Scale (VAS) for pain, and Short Form 36 (SF-36) scores at multiple time points up to 48 months.
Main Results:
- Significant improvements were observed in NDI scores, VAS pain scores (neck and arm), and SF-36 physical and mental component scores (p<0.001).
- 80% of patients reported satisfaction with the treatment.
- One case of neck hematoma requiring evacuation and one case of Horner's syndrome (with recovery) were reported. No implant-related complications or reoperations occurred.
Conclusions:
- The Prestige LP cervical disc implant is safe and effective for one- and two-level ACDR.
- ACDR with the Prestige LP system leads to significant improvements in pain and function for patients with degenerative disc disease.
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