Related Experiment Video
Updated: Apr 19, 2026

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Silanetriols as Powerful Starting Materials for Selective Condensation to Bulky POSS Cages
Natascha Hurkes1, Clemens Bruhn1, Ferdinand Belaj2
1Universität Kassel , Institut für Chemie und CINSaT, Heinrich-Plett-Straße 40, 34132 Kassel, Germany.
Abstract:
Controlled condensation reactions of tertiary silanetriols CH3(CH2) (CH3)2CSi(OH)3 (1b-f; n = 1-5) in the presence of trifluoroacetic acid and the hydrolysis of CH3(CH2)6(CH3)2CSiCl3 (3) lead to the selective formation of the corresponding disiloxane tetrols [CH3(CH2) (CH3)2CSi(OH)2]2O (2b-g; n = 1-6) in good yields. The TBAF-driven condensation reactions of the silanetriols CH3(CH2) (CH3)2CSi(OH)3 (1a-c; n = 0-2) as well as of the disiloxane-1,1,3,3-tetrol 2d (n = 3) yield in the selective formation of the first T8 cages bearing tertiary carbon substituents, CH3(CH2) (CH3)2C (4a-d; n = 0-3), which was not possible via the condensation of their alkoxysilane counterparts so far. The resulting compounds 2b-g and 4a-d have been characterized by multinuclear NMR, MS, and single-crystal X-ray diffraction.
More Related Videos
07:50Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
12:30Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Related Concept Videos
Ketones with Nonenolizable Aromatic Aldehydes: Claisen–Schmidt Condensation
As the self-condensation of ketones is generally not favored in basic conditions, the self-condensed products do not form in the reaction between ketones and benzaldehyde. The general reaction of Claisen–Schmidt...
Aldol Condensation vs Claisen Condensation
Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation
C–C Bond Formation: Aldol Condensation Overview
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
Esters to β-Ketoesters: Claisen Condensation Mechanism