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Published on: December 6, 2021
Tandem catalysis of amines using porous graphene oxide
Chenliang Su1, Rika Tandiana, Janardhan Balapanuru
1Department of Chemistry, Graphene Research Centre, National University of Singapore , 3 Science Drive 3, Singapore 117543, Singapore.
Abstract:
Porous graphene oxide can be used as a metal-free catalyst in the presence of air for oxidative coupling of primary amines. Herein, we explore a GO-catalyzed carbon-carbon or/and carbon-heteroatom bond formation strategy to functionalize primary amines in tandem to produce a series of valuable products, i.e., α-aminophosphonates, α-aminonitriles, and polycyclic heterocompounds. Furthermore, when decorated with nano-Pd, the Pd-coated porous graphene oxide can be used as a bifunctional catalyst for tandem oxidation and hydrogenation reactions in the N-alkylation of primary amines, achieving good to excellent yields under mild conditions.
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