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Published on: November 5, 2019
What is hiding behind bubbles of air? An unusual Streptococcus pyogenes meningitis
Paolo Gritti1, Andrea Luigi Lanterna1, Tatyana Sarnecki1
1Department of Anaesthesia and Intensive Care, Papa Giovanni XXIII Hospital; Neurosurgery Unit, Department of Neurosurgery and Neurological Sciences, Papa Giovanni XXIII Hospital; Bergamo, Italy; Faculty of Health, Medicine, and Life Science, Maastricht University, Maastricht, The Netherlands; Department of Neuroradiology, Papa Giovanni XXIII Hospital; Section of Infectious Diseases, Department of Clinical Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Abstract:
Streptococcus pyogenes is a rare but aggressive cause of meningitis, which often evolves in a poor outcome with fatal consequences. Although lumbar puncture and CT scan of the brain are the gold standard of diagnosis of cerebral infections, they can have some limitations. We report and describe the clinical history and neuroimaging of a 36-year-old woman admitted to the emergency department of our hospital three days after the onset of earache and otorrhoea. When the patient developed an emergent refractory status epilepticus, the CT scan of the brain showed an unusual pneumocephalus. However, the MRI study of the brain revealed a pachymeningitis with partial thrombosis of the right transverse sinus and subdural empyema due to a S. pyogenes otitis media. Prompt diagnosis and the specific findings of the MRI allowed rapid correct treatment and thus led to a good outcome for the patient.
Insights
Streptococcus pyogenes meningitis is aggressive but treatable. Prompt MRI revealed subdural empyema, enabling swift intervention and a positive outcome for this rare case.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Streptococcus pyogenes is a rare but aggressive cause of meningitis.
- Standard diagnostic tools like lumbar puncture and CT scans have limitations in diagnosing cerebral infections.
Observation:
- A 36-year-old woman presented with earache, otorrhoea, and refractory status epilepticus.
- Initial CT scan showed unusual pneumocephalus.
- MRI revealed pachymeningitis, right transverse sinus thrombosis, and subdural empyema.
Findings:
- The subdural empyema was attributed to Streptococcus pyogenes otitis media.
- MRI provided specific findings crucial for diagnosis.
Implications:
- Early and accurate diagnosis via MRI is critical for managing S. pyogenes meningitis.
- This case highlights the importance of advanced neuroimaging in complex neurological infections.
- Prompt treatment based on MRI findings can lead to favorable patient outcomes.
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Acute Pyelonephritis I: Introduction
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.

