Related Experiment Video
Updated: Apr 19, 2026
07:27
Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
12.6K
Behcet disease and pregnancy
A N C Gungor1, G Kalkan, S Oguz
1Canakkale 18 March University Hospital, Obstetrics and Gynecology Department, Turkey. dr_aysecakir@hotmail.com
Clinical and Experimental Obstetrics & Gynecology
|January 2, 2015
Summary
Women with Behcet disease (BD) experience higher miscarriage rates and deliver smaller babies compared to healthy individuals. Placental vasculitis may contribute to these adverse pregnancy outcomes in BD patients.
Area of Science:
- Reproductive Medicine
- Immunology
- Obstetrics
Background:
- Behcet disease (BD) is a multisystemic vasculitis often diagnosed during reproductive years.
- Understanding its impact on pregnancy is crucial for patient management.
Purpose of the Study:
- To investigate the relationship between Behcet disease and pregnancy outcomes.
- To compare pregnancy outcomes in BD patients versus healthy controls.
Main Methods:
- A multicenter retrospective survey study.
- Compared pregnancy outcomes of 94 BD patients (298 pregnancies) with 95 healthy controls (219 pregnancies).
Main Results:
- BD patients had significantly lower mean birth weight (3,214g vs. 3,351g, p=0.028).
- Higher miscarriage rates were observed in the BD group.
- No significant difference in hypertension or preeclampsia rates (12.8% vs. 11.6%, p=0.489).
Conclusions:
- Behcet disease is associated with delivering smaller babies and increased miscarriage rates.
- Placental vasculitis is a potential cause for these adverse outcomes in BD pregnancies.
Related Concept Videos
01:26Sexually Transmitted Infections
1.8K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.8K
01:27Cytomegalovirus Disease
71
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
71
01:25Hepatitis
63
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
63
01:27Acne Infection
75
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
75
01:07Teratogenicity
4.6K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.6K
01:24Disorders of the Female Reproductive System
4.9K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
4.9K