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Published on: December 9, 2014
Exercise for falls prevention in Parkinson disease: a randomized controlled trial
Colleen G Canning1, Catherine Sherrington2, Stephen R Lord2
1From the Clinical and Rehabilitation Sciences Research Group, Faculty of Health Sciences (C.G.C., N.E.A., S.M.M., S.D.O., J.S.), The George Institute for Global Health, Sydney Medical School (C.S., S.S.P.), Sydney School of Public Health (K.H.), and Sydney Medical School (S.H., V.S.C.F.), The University of Sydney, Australia; Neuroscience Research Australia and University of New South Wales (S.R.L.), Sydney; Prince of Wales Clinical School, University of New South Wales, and Neuroscience Research Australia (J.C.T.C.), Sydney; Department of Epidemiology and Preventive Medicine (S.H.), Monash University, Melbourne; Department of Statistics (G.Z.H.), Macquarie University, and Statistics Division, The George Institute for Global Health, Sydney; Department of Aged Care (M.D.L.), Royal Prince Alfred Hospital, Sydney; and Movement Disorders Unit (V.S.C.F.), Department of Neurology, Westmead Hospital, Sydney, Australia. colleen.canning@sydney.edu.au.
A 6-month exercise program for Parkinson disease patients did not reduce overall fall rates. However, it improved physical and psychological health, particularly in those with milder disease severity.
Area of Science:
- Neurology
- Gerontology
- Rehabilitation Medicine
Background:
- Parkinson disease (PD) is a neurodegenerative disorder characterized by motor symptoms including gait disturbances and balance impairment, leading to increased fall risk.
- Falls in PD patients contribute to injuries, reduced mobility, and decreased quality of life.
- Targeting modifiable fall risk factors through exercise is a potential strategy for fall prevention in PD.
Purpose of the Study:
- To evaluate the efficacy of a minimally supervised exercise program in preventing falls in individuals with Parkinson disease.
- To assess the program's impact on specific fall risk factors such as balance, leg strength, and freezing of gait.
Main Methods:
- A randomized controlled trial involving 231 Parkinson disease patients.
- Participants were assigned to either an exercise group or a usual-care control group.
- The exercise group engaged in 40-60 minute sessions, 3 times weekly for 6 months, focusing on balance, strength, and gait.
Main Results:
- No significant difference in overall fall rates or proportion of fallers between the exercise and control groups.
- A significant reduction in falls was observed in the subgroup with lower disease severity (IRR = 0.31, p < 0.001).
- The exercise group showed significant improvements in physical performance (Short Physical Performance Battery, sit-to-stand), fear of falling, affect, and quality of life compared to controls.
Conclusions:
- Minimally supervised exercise targeting balance, strength, and gait did not reduce overall fall rates in Parkinson disease patients.
- The exercise intervention demonstrated benefits in physical and psychological health, especially for individuals with milder PD.
- Disease severity is a critical factor influencing exercise effectiveness for fall prevention in Parkinson disease.

