Intraoperative diagnosis of glioblastomamultiforme with oligodendroglial and sarcomatous components

Glioblastoma, the most frequent primary brain tumor and the most malignant neoplasm, can have the most heterogeneous morphological presentation. Along with classical morphological features, areas of oligodendroglial component and mesenchymal differentiation may be seen. The present case was a rare case of glioblastoma presenting with sarcomatous and oligodendroglial components. The case was diagnosed intraoperatively by squash and touch cytology and later on confirmed by histopathological study.